Start 'Em & Sit 'Em is the ultimate look at the weekly NFL matchups and how they'll affect your fantasy football team. Sleeper alert features an under-the-radar player who could produce good numbers. Owners beware features a regular fantasy starter who could fail to meet expectations based on the strength of his opponent. Obvious fantasy starters like Peyton Manning and LeSean McCoy will not be featured. For your final lineup decisions, check our lineup rankings.
Start of the Week
Randall Cobb vs. New York Jets: Cobb had a nice start to the regular season, posting 58 yards, one touchdown and 11.80 fantasy points against a tough Seahawks defense on the road. He has a much more attractive matchup in Week 2, as Cobb will face a Jets pass defense that could be without its top cornerback, Dee Milliner, for another week. Look for Aaron Rodgers, Jordy Nelson and Cobb to make some noise for owners.
Start 'em
Vincent Jackson vs. St. Louis Rams: Jackson didn't have a great start to the season, posting just 36 yards with no touchdowns in Tampa's opener against the Carolina Panthers. He's still a nice option for owners, though, as Jackson has found the end zone three times in his last four home games. Also keep in mind that the Rams allowed the third-most fantasy points to wide receivers in Week 1, so the matchup is a good one.
Michael Floyd at New York Giants: Is the torch being passed in Arizona? Floyd is looking like the better fantasy wideout compared to Larry Fitzgerald, who caught just one pass in Week 1. Regardless, Floyd's matchup against the Giants is a favorable one. Their defense allowed the second-most fantasy points to receivers last week, so the Cardinals will look to exploit that weakness often in a one-time NFC East matchup.
Emmanuel Sanders vs. Kansas City Chiefs: Sanders didn't find the end zone last Sunday night against the Indianapolis Colts, but he was targeted nine times and hauled in six catches for 77 yards. This week he goes up against the Chiefs, who have one of the more questionable defensive backfields in the league, so Sanders is a good bet to produce. Consider him a borderline No. 2 or 3 fantasy wideout in this AFC West contest.
Sleeper alert - Brandin Cooks at Cleveland Browns: Cooks isn't a traditional sleeper at this point, as he went off for 95 scrimmage yards, one touchdown and 15.50 fantasy points against the Atlanta Falcons. Next on the schedule is a date with the Browns, who allowed the fifth-most fantasy points to wideouts a week ago. If Joe Haden is sent to shut down Marques Colston, Cooks would have a major advantage. He's a nice third receiver.
Sit of the Week
Eric Decker at Green Bay Packers: This one is less about the matchup and more about the fact that I just don't believe in Decker as a reliable fantasy receiver in New York. In his opener, the veteran out of Minnesota posted five receptions and just 7.4 fantasy points. Until he starts to post more impressive totals with Geno Smith under center, Decker just isn't someone I would trust as more than a No. 3 wide receiver.
Sit 'em
Victor Cruz vs. Arizona Cardinals: Cruz has become a real risk from a fantasy perspective, and his lack of Week 1 production was a reminder. Next up he faces the Cardinals, who have one of the NFL's better defensive backfields. Cruz has also struggled at home, posting fewer than 55 yards in five of his last six game at MetLife Stadium. Furthermore, the veteran hasn't scored a touchdown on his home turf since Dec. 2012.
Mike Wallace at Buffalo Bills: Wallace was impressive against Darrelle Revis and the New England Patriots, putting up seven catches, 81 yards and one touchdown in Week 1. So while he will be in most starting lineups moving forward, be sure to keep this in mind ... in his last eight road games, Wallace has recorded fewer than 50 yards six times. He's also scored twice in his last 11 games away from his home turf.
Jeremy Maclin at Indianapolis Colts (Mon.): Maclin posted a nice stat line (15.70 fantasy points) against the Jacksonville Jaguars in Week 1, but he'll have a much tougher matchup in Indianapolis on Monday night. The Colts were tough on the Broncos wideouts in their opener, holding Demaryius Thomas to 4.8 fantasy points and Denver wideouts to a mere 15.20 points overall. That makes Maclin less attractive in all fantasy circles.
Owners beware - Roddy White at Cincinnati Bengals: Chances are, you're going to be starting White this week. Just keep this little nugget in mind if you're in a touchdown-based league: During his entire career, White has scored just two touchdowns in 18 road games against the AFC. Two. He's also recorded 100-plus yards in just four of those contests. Take that little nugget for what it is ... plus, the Bengals are tough at home.
Michael Fabiano is an award-winning fantasy football analyst on NFL.com and NFL Network and a member of the Fantasy Sports Writers Association (FSWA) Hall of Fame. Have a burning question on anything fantasy related? Tweet it to _**@MichaelFabiano**_ or send a question via **Facebook**!