Details: Saturday, 10:30 p.m. ET, ESPN
What's at stake? The Cardinal can clinch the Pac-12 North with a win here. Cal's season has come unglued with four losses in the last five weeks, but a win at Stanford would certainly signal the end of the skid for star QB Jared Goff and the Golden Bears.
Matchup to watch: Stanford RB Christian McCaffrey vs. Cal LB Hardy Nickerson.

Game picks:
Brandt: Stanford, 41-27
Brooks: Stanford, 28-20
Davis: Stanford, 55-40
Goodbread: Stanford, 28-24
Jeremiah: Stanford, 34-31
Reuter: Stanford, 34-24
Zierlein: Stanford, 31-21

Details: Saturday, 3:30 p.m. ET, FS1
What's at stake? Rivalry pride, and not much else. Two disappointing seasons that already have combined for 10 losses make this game important only on the campuses involved.
Matchup to watch: Arizona DB Will Parks vs. Arizona State WR D.J. Foster.

Game picks:
Brandt: Arizona State, 44-30
Brooks: Arizona State, 30-27
Davis: Arizona State, 38-27
Goodbread: Arizona State, 44-38
Jeremiah: Arizona State, 31-24
Reuter: Arizona, 35-27
Zierlein: Arizona State, 42-31

Details: Saturday, 3:30 p.m. ET, ESPN
What's at stake? The Trojans can win the Pac-12 South by closing out the season with a win here and another over rival UCLA. Given the distractions of the season for USC, a Pac-12 title game appearance would be an impressive way to finish the year. Oregon needs help to stay alive in the Pac-12 race.
Matchup to watch: Oregon RB Royce Freeman vs. USC LB Su'a Cravens.

Game picks:
Brandt: Oregon, 42-38
Brooks: USC, 28-27
Davis: Oregon, 40-35
Goodbread: Oregon, 30-21
Jeremiah: Oregon, 35-24
Reuter: Oregon, 34-31
Zierlein: Oregon, 34-30

Details: Saturday, 7 p.m. ET, ESPN
What's at stake? Arkansas has won four games in a row and has plenty of momentum, but, like Mississippi State, the Razorbacks are basically playing for bowl position now.
Matchup to watch: Mississippi State DL A.J. Jefferson vs. Arkansas OL Denver Kirkland.

Game picks:
Brandt: Arkansas, 30-23
Brooks: Arkansas, 23-22
Davis: Arkansas, 28-25
Goodbread: Mississippi State, 33-30
Jeremiah: Arkansas, 21-20
Reuter: Arkansas, 38-28
Zierlein: Mississippi State, 28-27

Details: Saturday, 3:30 p.m. ET, FOX
What's at stake? The Utes need to win here and hope for a USC loss to Oregon in order to take the Pac-12 South. The Bruins, meanwhile, could potentially have a 10-3 season despite a myriad of injuries.
Matchup to watch: UCLA RB Paul Perkins vs. Utah LB Jared Norris.

Game picks:
Brandt: UCLA, 28-27
Brooks: Utah, 21-17
Davis: UCLA, 35-34
Goodbread: UCLA, 28-24
Jeremiah: Utah, 34-28
Reuter: Utah, 41-24
Zierlein: Utah, 28-27

Details: Saturday, 3:30 p.m. ET, CBS
What's at stake? LSU has gone from a championship contender to a fast-fading two-loss team in two weeks. Will the Tigers fold? Ole Miss needs unlikely help from Auburn to stay in the SEC West race.
Matchup to watch: LSU OL Vadal Alexander vs. Ole Miss DL Robert Nkemdiche.

Game picks:
Brandt: LSU, 28-27
Brooks: LSU, 17-14
Davis: LSU, 21-20
Goodbread: LSU, 23-21
Jeremiah: Ole Miss, 24-21
Reuter: Ole Miss, 24-21
Zierlein: Ole Miss, 28-24

Details: Saturday, 8 p.m. ET, ABC
What's at stake? The Sooners can make another strong push for playoff consideration with a win here. For TCU, it could be without its two best players. Receiver Josh Doctson has been ruled out for the rest of the regular season, and QB Trevone Boykin is a game-time decision. Can a one-loss TCU team get back into the College Football Playoff picture with a win over OU? By itself, that's doubtful, TCU still has another chance to impress next week against Baylor.
Matchup to watch: Oklahoma CB Zack Sanchez vs. TCU WR Kolby Listenbee.

Game picks:
Brandt: Oklahoma, 45-24
Brooks: Oklahoma, 34-27
Davis: Oklahoma, 48-41
Goodbread: Oklahoma, 41-30
Jeremiah: Oklahoma, 41-28
Reuter: Oklahoma, 45-27
Zierlein: Oklahoma, 42-23

Details: Saturday, Noon ET, ABC
What's at stake? A classic Big Ten battle here, but one with no real ramifications on the league title. Still, a home win over Michigan would put an entirely different spin on the Nittany Lions' season, and the perception of both coach James Franklin and quarterback Christian Hackenberg.
Matchup to watch: Michigan DB Jourdan Lewis vs. Penn State WR Chris Godwin.

Game picks:
Brandt: Michigan, 17-16
Brooks: Michigan, 23-20
Davis: Penn State, 28-24
Goodbread: Michigan, 20-13
Jeremiah: Michigan, 24-21
Reuter: Michigan, 31-17
Zierlein: Michigan, 24-17

Details: Saturday, 7:30 p.m. ET, FOX
What's at stake? Baylor will be looking to upend the Big 12's last remaining unbeaten team. The Cowboys can't afford a loss -- they saw last year how the CFP selection committee views one-loss Big 12 teams.
Matchup to watch: Baylor CB Xavien Howard vs. Oklahoma State WR James Washington.

Game picks:
Brandt: Oklahoma State, 45-31
Brooks: Oklahoma State, 44-41
Davis: Baylor, 50-49
Goodbread: Baylor, 45-40
Jeremiah: Baylor, 41-35
Reuter: Oklahoma State, 52-48
Zierlein: Baylor, 35-34

Details: Saturday, 3:30 p.m. ET, ABC
What's at stake? The Big Ten East is on the line here, and so is a chance to join the playoff field. There isn't a bigger game in the country, and the Spartans should provide the toughest test OSU has faced this season.
Matchup to watch: Michigan State QB Connor Cook vs. Ohio State DB Vonn Bell.

Game picks:
Brandt: Ohio State, 27-13
Brooks: Ohio State, 20-17
Davis: Ohio State, 34-20
Goodbread: Michigan State, 27-24
Jeremiah: Ohio State, 27-21
Reuter: Ohio State, 31-24
Zierlein: Ohio State, 30-20