Another top-notch runner is out for the season, and the next is only one bad step away. Michael Fabiano says now is the time to handcuff your backs.

J.P. Losman, Peerless Price, Anthony Henry and Terry Glenn are the top inactives for Monday night's battle between Dallas and Buffalo.

Major injuries continue to mount across the NFL. We examine all the latest news and notes in our fantasy injury news report.

Week 4 inactives

Several players suffered major injuries last week. Our fantasy injury report has all the latest news and examines how these ailments will affect your team.

Week 3 inactives

Andre Johnson is out with an injured knee, but two prominent quarterbacks could be back under center in Week 3.

Several impact players sustained injuries in Week 1. Michael Fabiano examines all the implications in our fantasy injury report.

Week 1 inactives