It was over when ...
Colts QB Peyton Manning had a pair of TDs and an INT in the win.
(Michael Conroy / Associated Press)
Game ball
The Colts offense grabs all of the headlines, but DE Robert Mathis had a monster game leading the defense. Mathis had three sacks and forced two fumbles as the Seahawks offense was quiet for most of the afternoon.
Key Stat
Seahawks QB Seneca Wallace completed more passes, but only averaged 4.6 yards per pass play. Colts QB Peyton Manning nearly doubled that with 8.6 yards per pass play.
Noteworthy
The Colts have won 13 consecutive regular-season games, the longest current streak in the NFL. The Colts lost to the Chargers in the wild-card round of the playoffs last season. ... Colts rookie WR Austin Collie caught his first touchdown, a 21-yarder at the end of the first half ... Seahawks WR T.J. Houshmandzadeh (eight receptions for 103 yards) topped 100 receiving yards for the first time this season.