Start 'Em & Sit 'Em is the ultimate look at the weekly NFL matchups and how they'll affect your fantasy football team. Sleeper alert features an under-the-radar player who could produce good numbers. Owners beware features a regular fantasy starter who could fail to meet expectations based on the strength of his opponent. Obvious fantasy starters like Aaron Rodgers and Adrian Peterson will not be featured. For your final lineup decisions, check our lineup rankings.
Byes:Tom Brady, Jason Campbell, Alex Smith, Geno Smith
Start of the week
Philip Rivers vs. Denver Broncos: This AFC West showdown has the look of a massive shootout in the stat sheets, so Rivers is an attractive option in fantasy land. Further adding to his appeal this week is the fact that the Broncos have given up more fantasy points (27.1 PPG) to quarterbacks on the road than any team in the NFL. (Maximum value: High QB1)
Harrison: Week 10 Power Rankings
Start 'em
Russell Wilson at Atlanta Falcons: Wilson hasn't been as productive in even-numbered weeks this season, but I'm looking past that odd trend and focusing on the matchup in Atlanta instead. The Falcons have allowed the third-most fantasy points (21.6 PPG) to opposing quarterbacks at home, so Wilson should shine in the Georgia Dome. (Maximum value: Mid QB1)
Colin Kaepernick vs. Carolina Panthers: No team has allowed fewer fantasy points to quarterbacks on the road than Carolina, but that stat is deceiving -- the Panthers have faced E.J. Manuel, Carson Palmer, Matt Cassel and Mike Glennon on the road. That's not exactly the who's who of fantasy stars. Start Kaepernick with confidence. (Maximum value: Low QB1)
Ben Roethlisberger vs. Buffalo Bills:Big Ben hasn't had the most consistent season in the stat sheets, but he is coming off a monster performance against the New England Patriots. Next up are the Bills, who have allowed six quarterbacks to score 19-plus fantasy points against them in 2013. He's still a free agent in a lot of NFL.com leagues. (Maximum value: Low QB1)
Sleeper alert - Jake Locker vs. Jacksonville Jaguars: Locker has been hot lately, scoring 19-plus fantasy points in three of his last four starts. He should continue to put up a nice numbers this weekend against the Jaguars, who have surrendered an average of over 20 fantasy points per game to signal-callers on the road this season. (Maximum value: Low QB1)
Sit of the week
Terrelle Pryor at New York Giants: Pryor was on his way to a big stat line last week before injuring his knee, but the ailment shouldn't keep him out of action this week. Regardless, he's a bit of a risk against the Giants -- their defense has surrendered an average of just 9.23 fantasy points to quarterbacks in the last four weeks. (Maximum value: High QB2)
Sit 'em
Andy Dalton at Baltimore Ravens: Dalton was one of the hottest quarterbacks in fantasy football, but last week's stinker against the Miami Dolphins put that streak to bed. He's in danger of posting another poor stat line against the Ravens, who have surrendered an average of just 10.8 fantasy points per game to quarterbacks at home. (Maximum value: High QB2)
Case Keenum at Arizona Cardinals: Keenum has been white hot since taking over the starting job in Houston, but can you trust him to post strong numbers in a tough road game against the Cardinals? Their pass defense has been tough in 2013, allowing an average of just 13.4 fantasy points per game to opposing quarterbacks on their home field. (Maximum value: High QB2)
Carson Palmer vs. Houston Texans: If interceptions were fantasy gold, Palmer would be one of the richest quarterbacks in the NFL. Unfortunately for the veteran, his tendency to throw picks plus a bad matchup against the Texans makes him a sit 'em. Houston has allowed the sixth-fewest fantasy points (14 PPG) to quarterbacks on the road. (Maximum value: Mid QB2)
Owners beware - Matt Ryan vs. Seattle Seahawks: You probably have to start Ryan this week, but I would temper expectations. He's thrown seven interceptions in his last two starts, and a game versus Seattle isn't at all favorable. In fact, their defense has given up the third-fewest fantasy points (12.8 PPG) to quarterbacks on the road. (Maximum value: Low QB1)
Michael Fabiano is an award-winning fantasy football analyst on NFL.com and NFL Network and a member of the Fantasy Sports Writers Association (FSWA) Hall of Fame. Have a burning question on anything fantasy related? Tweet it to **@Michael_Fabiano** or send a question via **Facebook**!