The NFL season officially begins in earnest this week with the start of the preseason for all 32 teams. Around The NFL's Conor Orr dissects what you can expect to see from the 16 games this weekend.
Here's what to what to watch for ...
Indianapolis Colts at Buffalo Bills (7 p.m.)
» Where is the Ryan defense at? An offseason of change and devastating injury has Buffalo looking to put all the pieces together. Rex Ryan has never been afraid to get exotic in the preseason, but does he have enough institutional knowledge to run what he wants?
» How careful will Chuck Pagano be with Andrew Luck? This has been an important season for the former No. 1 overall pick, and he will get to begin anew on Saturday. The Colts planned on playing Luck in the Hall of Fame game, so nothing should change but the opponent.
» Hassan Ridgeway has been seeing some first-string love following the suspension of Colts tackle Arthur Jones. While that might not be a permanent fixture once the lineup settles into order, Buffalo's offensive line will provide an adequate proving ground.