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| Player | Cause | Organization |
|---|---|---|
| Nick Allegretti | Disease Awareness/Prevention | Uplifting Athletes |
| Orlando Brown | Diabetes | JDRF |
| Harrison Butker | Military Appreciation and FUP60 | Wounded Warrior Project |
| Mike Danna | Disease Awareness/Prevention | Sisters Network |
| Mecole Hardman | Autism | Friends Helping Friends Club Inc. |
| Chad Henne | Breast Cancer | Breast Cancer Support Services of Berks |
| Tyreek Hill | Hunger Relief | Tyreek Hill Family Foundation |
| Chris Jones | Diabetes Treatments, Prevention and Research | JDRF, Juvenile Diabetes Research Foundation |
| Travis Kelce | Youth Education | Eighty-Seven and Running Foundation |
| Kyle Long | Providing Clean, Accessible Drinking Water to Communities in Need | The Chris Long Foundation |
| Patrick Mahomes | 15 and the Mahomies Foundation | 15 and the Mahomies Foundation |
| Tyrann Mathieu | Youth Education | Tyrann Mathieu Foundation |
| Derrick Nnadi | Community Outreach | Derrick Nnadi Foundation |
| Alex Okafor | Cancer & Anti Violence | LLS & Bakari Foundation |
| Cornell Powell | Cancer | Breast Cancer |
| L'Jarius Sneed | Youth Mentorship | Big Brothers Big Sisters |
| Andrew Wylie | Military Appreciation/Support | Signatures For Soldiers |