San Francisco 49ers cornerback linebacker Patrick Willis (hamstring) and cornerback Carlos Rogers (knee) were both listed as questionable on Friday's injury report, potentially leaving San Francisco without two key defenders for Sunday's divisional matchup.
While Rogers was limited for a second straight day, Willis' was unable to practice this week, leaving his status in serious doubt for Sunday's game at Arizona.
Wide receiver Braylon Edwards, who sat out last week's victory over St. Louis with shoulder and knee injuries, was also listed as questionable but is expected to play Sunday, according to the San Francisco Chronicle.
The 49ers have been evasive on the severity of Willis' injury, with coach Jim Harbaugh refusing to elaborate on an MRI exam several times Wednesday by saying, "Wouldn't share any information about it."
For a complete look at all injuries around the league, visit NFL.com's injuries page.