Run-heavy offense: The 49ers are one of just three NFL teams (Dallas, New England) to have more run attempts than pass attempts.
Issues with the run: Despite the high volume of carries, San Fransisco is averaging just 3.6 yards per carry (T-24th in NFL).
Dink and dunk: No team averages fewer yards per pass attempt than the 49ers, who average just 6.1 yards per attempt.
Starting LB returns:49ers starting linebacker Aaron Lynch will make his season debut on Thursday. He was suspended during the first four weeks of the season (substance abuse).
New voice on defense: With NaVorro Bowman out for the year (torn Achilles), Nick Bellore will be the starting MIKE linebacker for the 49ers. This will be Bellore's first career start.
Key matchup: The 49ers have allowed just nine QB hits this season (T-2nd fewest in league). The Arizona defense has 11.0 sacks this season (T-6th most in league).
