It was over when ...
Bryant Johnson scored on a 2-yard touchdown reception with less than a minute left in the first half to put the 49ers up 35-3. Despite a bevy of San Francisco mistakes in the second half, St. Louis was never able to threaten for the lead.
Game ball
Niners QB Shaun Hill was extremely efficient in his second start of the season and excelled in reading the Rams' defensive looks and getting the offense into the right play.
Key stat
San Francisco scored touchdowns on all five of its trips to the red zone. The primary reason for why it was able to put away St. Louis so early.
Noteworthy
Mike Singletary got his first career win as coach of the 49ers. ... Walt Harris had a sack and interception in the same game for the first time in his 13-year career. ... Rams RB Antonio Pittman rushed for a career-high 95 yards. ... St. Louis' Jason Craft had one career sack entering the game, but had two Sunday.