In Brief
» Last meeting: Buffalo eschewed a field goal from the Tennessee 28 and went for it on fourth-and-5 with less than a minute to go. J.P. Losman was intercepted on the play, allowing the Titans to claim a 30-29 victory in Week 16 of the 2006 season.
» Streaks: The Titans have won five of the past six meetings and possess a 25-16 overall series edge, including the playoffs.
» Last week: Four takeaways by the defense enabled Tennessee to emerge from San Francisco with a 34-27 win. ... Buffalo was on a bye.
Keep your eye on ...
T.O.'s production: It has been a disappointing season for the flamboyant receiver so far. He is on pace for his lowest total of receptions, yards and touchdowns since his rookie season. If he is to ever break out in a Bills uniform, this could be the week as he faces the Titans' league-worst pass defense.
Vince Young's steady play: Since regaining the starting job in Week 8, Young has looked like a different player. Gone are the mistakes, poor decisions and erratic throws of his past. If he can keep up his solid, if unspectacular, play, that would give the Titans a huge boost.
Did you know?
The Bills are 14-6 all-time after a bye. ... Buffalo ranks second in the NFL with 15 interceptions. ... Young has won six consecutive games as a starter. ... Titans RB Chris Johnson leads the NFL in rushing with 491 yards.