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Quick Take: Chargers (3-3) at Bills (4-1)

Last meeting
On a windy afternoon in Buffalo, LaDainian Tomlinson rushed for 178 yards and two touchdowns in a 24-21 Chargers win in 2006.

Streaks
The Chargers have beaten the Bills in six of the last eight matchups, and lead the overall series, 20-9-2.

Last week
Philip Rivers used solid protection to take advantage of a porous New England secondary, passing for 306 yards and three touchdowns in a 30-10 Chargers victory. ... The Bills had a bye.

Keep your eye on ...
Edwards' post-concussion play:Bills QB Trent Edwards is expected to play Sunday, having had two weeks to recover from a concussion suffered in the first quarter of Week 5. Edwards had been solid during the first four weeks of the season, completing 66.4 percent of his passes with four touchdowns and two interceptions.

Philip's pocket: San Diego's success passing the ball against the Patriots was largely a product of its offensive line, which did not allow a single sack on Rivers in 27 pass attempts. The Bills, who are averaging just two sacks per game, could be without last year's sack leader Aaron Schobel, who is still recovering from a left foot injury.

Buffalo's secondary concern: San Diego's three passing plays of 40-plus yards against the Patriots (without Chris Chambers, no less) should be a little disconcerting for the Bills, who could be without a couple key defensive backs. Starting CB Terrence McGee is dealing with a sprained left knee, while safety Ko Simpson is recovering from a hamstring injury.

Did you know?
Since 2007, Chargers CB Antonio Cromartie leads the NFL with 12 interceptions. San Diego is 7-0 when Cromartie has an interception. ... The Bills are 2-0 under coach Dick Jauron following a bye week. ... Bills RB Marshawn Lynch has recorded a touchdown in four consecutive home games. He averages 89.7 rushing yards per game in Buffalo.

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