Why to watch
Arizona has been an interesting team lately, winning wild overtime games with some zany finishes. The 49ers clinched the division, but are trying to hold onto the NFC's No. 2 seed.
Inside story
San Francisco ran the ball 49 times in the first meeting between these teams, but the Cards' run defense has been much better the last few weeks. Beanie Wells is running as hard as anyone in the league right now. Don't kick to Patrick Peterson. WR Andre Roberts comes in off a breakout game against Dallas. If Larry Fitzgerald can get going early, the 49ers are not built to be great from behind.