No quarterback has ever thrown for 500+ yards in back-to-back games, and the odds aren't good for Derek Carr (coming off a 513-yard Week 8 performance against the Buccaneers). The Broncos are 1 of 2 teams (ARI) that has not allowed even 270 passing yards to any QB this season.

Since 2015, Khalil Mack and Von Miller have more sacks than any other NFL players. Mack's 20.0 sacks lead the league in that span, while Miller is just half a sack behind at 19.5. One quarter of Mack's total in that span (5.0 sacks) came in his last game against the Broncos.

Odell Beckham Jr. traditionally increases his production in the second half of the season. In Weeks 1-8, Beckham has averaged 77.2 receiving YPG, 15th- best in the NFL since he entered the league in 2014. In Weeks 9-17, Beckham averages 124.7 receiving YPG, not only the highest mark in the NFL in that span but the highest average by any player in Weeks 9-17 since 1970.

Matt Ryan leads the league in passing yards (2,636) and passing TD (19) this season. The last player to lead both categories in a season was Peyton Manning in 2013, who won the MVP award and took the Broncos to the Super Bowl.

Is Aaron Rodgers back? Rodgers is coming off back-to-back games with at least 3 TD passes and 0 interceptions for the first time since the 2014 season (Weeks 10-11), when the Packers went 12-4 and Rodgers won the MVP award.

The Browns passed on Cowboys QB Dak Prescott 8 times in the 2016 NFL Draft, including their selection of Cody Kessler 42 picks ahead of Prescott. The last time the Browns had a QB with a single-season passer rating as high as Prescott's 99.6 mark in 2016 was Milt Plum in 1960 (110.4).

What's wrong with the Vikings? For starters, Sam Bradford has been a sitting duck in the pocket in their last two games. Bradford was sacked 8 times in his first 4 starts combined (all wins), but has been sacked 11 times in the last two games (both losses).

The Seahawks are 9-1 in primetime home games under Pete Carroll (since 2010), winning those games by an average score of 28-13. Their only loss came in their last primetime home game, a 39-32 loss to the Cardinals in Week 10, 2015. Seattle is 4-0 under Carroll in Monday night home games.

Marcus Mariota has a touchdown-to-interception ratio of 25-0 in the red zone in his career. Among all active players with at least 50 pass attempts in the red zone, Mariota's 114.9 red zone passer rating ranks #1.

Jay Ajayi will attempt to do something that has never been done before in NFL history: rush for 200+ yards in 3-straight games. The player who came closest was O.J. Simpson, who rushed for 171 yards in 1976 after back-to-back 200- yard games.