The meeting between the Steelers and Seahawks will be played on Russell Wilson's 27th birthday. The only player in NFL history with more playoff wins than Wilson before his 27th birthday is his Week 12 opponent, Ben Roethlisberger (Roethlisberger eight, Wilson six). No player has more Super Bowl starts by age 27 than Wilson (tied with Roethlisberger and Tom Brady).

This game features the Patriots' top-ranked pass offense against the Broncos' top-ranked pass defense. The Broncos have allowed eight passing TDs this season, while Rob Gronkowski has caught eight of his own. Tom Brady is 6-0 in his career during the second half of the season when facing the league's top pass defense, with 11 TDs and 5 INTs.

Denver scored just 17 points in Brock Osweiler's first start last week after averaging 22.8 PPG with Peyton Manning at quarterback. But the Broncos gained more yards with Osweiler (389 vs 331.7 per game), were better on third down (42.9 vs 33.1 pct) and did not turn over the ball (2.1 per game in Manning's starts) in Week 11 with Osweiler under center.

If Jameis Winston continues to trend upward, he could soon see his named etched in rookie record books. He's currently on pace for 3,848 passing yards and 24 passing TDs, which would each rank third all-time for a rookie quarterback. Among all rookies selected No. 1 overall in NFL history, his 86.5 passer rating would be the best ever.

Eli Manning has started 177 straight games at quarterback, the longest active streak in the NFL. The Redskins have started 10 different quarterbacks over that span (John Beck, Mark Brunell, Jason Campbell, Todd Collins, Kirk Cousins, Robert Griffin III, Rex Grossman, Colt McCoy, Donovan McNabb and Patrick Ramsey).

The Browns beat the Ravens in Week 5, so Week 12 presents an opportunity for Cleveland's first sweep of a divisional opponent since they beat the 2007 Ravens twice. The 2002 Bengals are the only other AFC North team to be swept by the Browns since realignment in 2002. Both the 2002 Bengals (Dick LeBeau) and 2007 Ravens (Brian Billick) replaced their head coaches after being swept by Cleveland.

Alex Smith has never lost to an AFC East team in his career. His 7-0 record is the most wins without a loss vs the AFC East since 1970. The next closest is Bill Nelsen who was 4-0 vs AFC East since 1970.

The Cardinals have the league's top-ranked total and scoring offense. Conversely, the 49ers rank last in both total and scoring offense. This marks the 27th matchup since 1970 featuring the team with the league's top total and scoring offense against the team with the league's worst total and scoring offense. Teams with the top ranked offense are 20-5-1 in the previous 26 games.

The Saints have gained 300+ yards of total offense in 30-straight games, their longest such streak since at least 1970. The Vikings hold the record for the longest streak of 300+ yard games since 1970, doing so in 36 straight games between Week 4, 2002 and Week 8, 2004.

Thomas Rawls has not missed a beat in Marshawn Lynch's absence. Among all running backs with 100+ carries this season, Rawls' 6.0 yards per carry is tops in the NFL. His 209 rushing yards vs the 49ers in Week 11 were more than Lynch has had in any game (college or pro), and the most by any undrafted rookie since at least 1960.