The Lions have lost 23 consecutive games (including playoffs) in Green Bay. Their last win came in 1991 when Erik Kramer defeated Mike Tomczak. Matthew Stafford was 3 years old at the time.

Andrew Luck has 22 giveaways this season, which is the second-most in the NFL behind Jay Cutler's 24. Since 1991, five QBs have led NFL in giveaways and made the postseason: Jim Kelly (1992), Brett Favre (1993), Drew Bledsoe (1994), Marc Bulger (2003) and Eli Manning (2007). Both Kelly and Manning advanced to the Super Bowl.

The NFC South Champion is guaranteed to finish the season below .500. Three teams in NFL history have made the playoffs with a losing record. The 2010 Seahawks are the only such team to win a playoff game.

The Falcons, who could win the NFC South beating Carolina on Sunday, are 5-0 against the NFC South and 1-9 against the rest of the NFL. The 11-4 Cardinals are only non-NFC South team that Falcons have defeated.

If John Harbaugh's Ravens do not make the playoffs, they will be only the eight Super Bowl winning team to miss the playoffs in each of the next two seasons. Harbaugh would join a group of coaches that includes Chuck Noll, Bill Parcells, Joe Gibbs, Jon Gruden and Tom Coughlin. All went at least two seasons without bringing their Super Bowl-winning teams back to the postseason.

Tom Brady and his #1 scoring offense will host the Bills and their #4 total defense Sunday. The Patriots have faced 3 teams currently ranked in the top 5 in total defense this season (DET, DEN and BUF). In those games, the Patriots have scored no fewer than 34 points and won each game by at least 15 points.

The Bills defense held arguably 2 of the top 3 MVP candidates at quarterback without a TD pass in Weeks 14 (Peyton Manning) and 15 (Aaron Rodgers). How will they fare against the third in Tom Brady on Sunday? Brady threw for 4 TD in Week 6 at Buffalo.

Ryan Tannehill needs 214 yards to be the only Dolphins QB other than Dan Marino to throw for 4,000 yards in a season. Marino accomplished the feat six times in his Hall of Fame career.

With a win at Washington, the Cowboys would be the first team since the 16-0 Patriots in 2007 to go undefeated on the road. Four of the last five teams to go undefeated on the road reached the Super Bowl with the 1984 and 1989 San Francisco 49ers hoisting the Lombardi Trophy.

Pittsburgh's 2014 offense with Ben Roethlisberger, Le'Veon Bell and Antonio Brown has surpassed single-season franchise marks in points per game (27.3), yards per game (415.4) and passing yards per game (300.5).

Odell Beckham Jr. is the first player in NFL history to have a 1,000-yard season after missing his team's first three games of the season (Beckham missed first four games). Beckham's 79 receptions are the most in NFL history for a player in his first 11 career games. His 1,120 receiving yards are most through a player's first 11 games in Super Bowl era (since 1966), and his 11 receiving TD are also the most through a player's first 11 games in that time.

With a win and the outcome of the Lions at the Packers not being a tie, the Seahawks will have home-field throughout the playoffs for the third time in franchise history. Each of the first two times, the Seahawks reached the Super Bowl (2005 and 2013).