DeMarco Murray is the fourth player in NFL history with 100+ rush yards and at least one rushing TD in each of the first four games of a season, joining Jim Brown, O.J. Simpson and Emmitt Smith. Only Brown (6 games) and Simpson (5 games) made it past Week 4.

Alex Smith and Colin Kaepernick have similar stats since the 49ers traded Smith to the Chiefs before the 2013 season. Smith is 13-6 in the regular season; Kaepernick is 14-6. Smith's comp. pct. of 61.6 compares to Kaepernick's 60.4, Smith's passer rating of 90.2 is 1.3 less than that of the 49ers QB. Smith has thrown 30 TDs, Kaepernick 27. Smith has thrown 10 INTs, Kaepernick 12.

The Bengals are allowing 11.0 PPG (best in NFL). If Cincinnati were to continue at that pace, it would be the best PPG allowed since the 2000 Baltimore Ravens (10.3 PPG, Super Bowl XXXV champions).

Each QB is excelling in different areas this season. Ben Roethlisberger has completed 57.1 pct of 20+ yard passes, the 2nd highest percentage in the NFL. Blake Bortles' completion percentage of 87.9 pct on passes of 5 or fewer air yards is the highest in the NFL (among QBs with at least 10 attempts).

Bortles' 78.4 comp. pct. in Week 4 was the highest completion percentage of any QB in his first start since 1960 (minimum 30 attempts).

Eli Manning is the New York football fan's Mr. October. Manning is 29-7 in October, for a winning percentage of 81.1 pct., his best of any month.

In 2011, Kirk Cousins and Russell Wilson squared off in two Big 10 matchups between Michigan State and Wisconsin. In the first game, Cousins and MSU won 37-31 on a Hail Mary that was initially ruled short of the end zone, but was overturned on replay. In the second game, Wilson won the MVP en route to 42-39 Wisconsin victory in the Big 10 Championship Game.

In the NFL's 95-year history, 1,249 players have thrown a touchdown pass, but Brett Favre (508) is the only player to reach the 500-touchdown mark. Denver's Peyton Manning, who has 499 career touchdowns in 17 seasons with Indianapolis and Denver, is on the verge of joining this exclusive club.

Joe Flacco has not been sacked in his last three games, the first three-game stretch of his career without a sack. The Ravens have never gone four straight games without allowing a sack.

Jordy Nelson and Randall Cobb have 698 receiving yards combined, the most in the NFL for any receiving duo. Nelson has 459 yards and Cobb has 239 yards. Through Week 4, Jordy Nelson has accounted for 45.6 pct. of the Packers' receiving yards, 38.4 pct. of their receptions and 38.0 pct. of their targets, ranking first in all those categories in the NFL.

Two teams remain undefeated: Arizona and Cincinnati are 3-0 and were on byes in Week 4. Since the playoffs expanded to 12 teams in 1990, 83.1 pct. of teams (59 of 71) that started the season 4-0 went on to make the playoffs.