The Falcons are the first team in NFL history to start a season 5-0 after trailing in the fourth quarter of at least four games. The Falcons have comeback wins against the Eagles, Giants, Cowboys and Redskins.

Colts quarterback Andrew Luck has lost all four games he's played against Tom Brady and the Patriots by a combined score of 189-73. The Patriots have scored at least 40 points in each of those games and have tallied 15 rushing TDs. The Patriots are one of the two teams Luck has faced multiple times in his career without a win. The other is the Jets, which Luck is 0-2 against.

During his last four seasons with the Saints, Seahawks tight end Jimmy Graham caught half of the 20-plus-yard passes thrown his way, including 10 for touchdowns. Quarterback Russell Wilson has yet to attempt a single pass of more than 20 yards to Graham this season.

Panthers quarterback Cam Newton already has 43 rushes for 195 yards and two TDs this season. That puts him on pace for 172 rush attempts, which would smash the NFL single-season quarterback record of 141 set by Bobby Douglass of the Bears in 1972.

Last season, the Cardinals averaged a league-low 3.29 yards per carry. This season, Arizona leads the league with 4.96 yards per rush. A big part of that is Chris Johnson, who is tied for second in the NFL with 405 rushing yards. Johnson is averaging 5.1 yards on the ground, his highest mark since averaging 5.6 yards per tote in 2009 on his way to 2,006 rushing yards.

This is a rematch of Super Bowl XLVII, which is remembered as the Harbaugh Bowl and for Ray Lewis' final game. It is also the only Super Bowl in which the two starting quarterbacks had not been selected to a Pro Bowl. In fact, Joe Flacco and Colin Kaepernick are still waiting to make their Pro Bowl debuts.

This is the seventh time in franchise history the Broncos have started 5-0. Five of the previous six times they made the Super Bowl. The Browns only have two wins in franchise history against teams 5-0 or better. They defeated the 5-0 Baltimore Colts in 1968 and the 6-0 Cowboys in 1969. The Broncos have won 10 straight games against the Browns, who are tied for the longest active win streak for one team against another.

The Bengals are ranked second in total offense entering Week 6. Bills Head Coach Rex Ryan has never defeated a team ranked second or higher in total offense. He is 0-6 has been outscored, 200-106, against those teams.

Matthew Stafford has a passer rating of 0.5 when targeting Calvin Johnson on passes of 15-plus air yards this season. Stafford had a passer rating of 82.9 when targeting Johnson on such passes last season.

Six NFL teams -- Falcons (5-0), Panthers (4-0), Bengals (5-0), Broncos (5-0), Packers (5-0) and Patriots (4-0) -- are undefeated through Week 5. The NFL record for the most 5-0 teams in a single season is five, which was set in 2009. Since the playoffs expanded to 12 teams in 1990, 29 of the 31 (93.5 percent) previous teams to start 6-0 made the playoffs.