Will the Giants continue to be kryptonite to the Cowboys? The Giants served Dallas 2 of its 3 losses in 2016, holding the Cowboys to 13 points and 294 total yards per game. Dallas averaged 28.2 PPG and 388.5 total YPG against all other teams. Prescott's 58.6 passer rating against the Giants was his worst against any team, and included a 0.0 mark when targeting Dez Bryant.

The NFL's best QB rivalry? How about Aaron Rodgers and Russell Wilson? Not only have they spearheaded the two winningest teams in the NFC since Wilson entered the league in 2012, but Rodgers (104.1) and Wilson (99.6) have the 2 highest career passer ratings among all QBs with 1,000+ pass attempts in NFL history. The last non Rodgers-Wilson meeting between the two highest-rated passers in league history? Steve Young vs. Joe Montana in Week 2, 1994 – when Montana's Chiefs defeated Young's 49ers 24-17.

Are the 2017 Patriots even better than last season's Super Bowl-winning team? Not only does New England get Rob Gronkowski back healthy, but it added a Pro Bowl CB (Stephon Gilmore), a WR coming off back-to-back 1,000-yard seasons (Brandin Cooks), and the NFL's 2016 yards per carry leader (Mike Gillislee).

Despite missing the entire 2016 season (retired), new Raiders running back Marshawn Lynch still has the most rushing touchdowns in the NFL since 2011 (51 TD).

Not only will DeShone Kizer be the 27th different starting QB for the Browns since 1999, he'll also be tied for the 3rd-youngest QB (21 years, 250 days old) to start in Week 1 since the 1970 merger. Only Drew Bledsoe and Matthew Stafford were younger when starting in Week 1 (in 1993 & 2009 respectively).

When Adrian Peterson faces the Vikings on Monday night, he'll be the 6th RB in NFL history to face a team he previously amassed over 10,000 rushing yards with. The previous 5 players to fit the bill (Steven Jackson, LaDainian Tomlinson, Fred Taylor, Emmitt Smith, Thurman Thomas) averaged just 14.4 rushing yards per game and 2.3 yards per carry in those games.

Jared Goff's 7 winless starts in 2016 mark the 2nd-longest losing streak to start a career by QB drafted with the #1 overall pick (Common Draft era). The QB with a longer such streak? Hall of Famer Troy Aikman, who went on to win 94 games and 3 Super Bowls after losing his first 11 NFL starts.

The Lions made Matthew Stafford the NFL's highest-paid player with a new 5- year, $135 million extension. Stafford's big payday came on the heels of an NFL single-season record (since 1950) eight 4th-quarter comebacks in 2016. However, he remains winless in the postseason (0-3) and 5-46 against teams to finish the season with a winning record.

The Jaguars had six individual 100-yard rushing games over the last 3 seasons, tied for 3rd-fewest in the NFL. In that same span, #4 overall pick Leonard Fournette had 19 games with 100+ rush yards at LSU, more than any NFL RB.

Since sacks became official in 1982, only 5 players had more sacks in their first 12 career games than Joey Bosa's 10.5. Bosa will get a firsthand look at one of those in Week 1, as Von Miller (11.5 sacks in first 12 career games) and the Broncos host the Chargers on Monday night.