If only every game were played in Denver, the rest of the NFL might stand a chance against Tom Brady. Brady is 3-7 in Denver (including playoffs) for a .300 winning percentage that is his worst in any city (min. 2 starts). In all other games, his winning percentage is .790 (211-56).

The Cowboys have five wins by double digits this season (including each of their last 3 games), tied for the most such wins in the NFL. Each of the last four Super Bowls featured a team at least tied for the most double-digit wins that season (2016 Patriots, 2015 Panthers, 2014 Seahawks, 2013 Broncos).

The Bills are above .500 at their season midway point for the fifth time since 2000. In those four previous instances, they combined to go 10-22 in the final 8 games, missing the playoffs each time.

This game features two QBs with polar-opposite styles. Among the 32 QBs with 20+ starts since 2015, Drew Brees ranks 1st in passing yards per game (315.2) and last in rushing yards per game (0.9) as a starter. Among the same group, Tyrod Taylor ranks last in passing yards per game (208.1) and 1st in rushing yards per game (36.6).

Among all players with 150+ pass attempts since Week 3, Kirk Cousins has the NFL's 3rd-highest passer rating (108.4, behind only Deshaun Watson & Carson Wentz). In that same span, the Vikings defense has allowed the 3rd-lowest rating (73.0).

The Rams are in line to become the first team in NFL history to jump from the league's worst scoring offense (14.0 PPG in 2016) to the best scoring offense (32.9 PPG in 2017). Their season-to-season improvement of 18.9 points per game is also the largest in NFL history.

Russell Wilson leads the Seahawks with 271 rushing yards this season. He is on track to become the fifth QB since the 1970 merger to lead his team in rushing yards, joining Cam Newton (2012), Donovan McNabb (2000), Randall Cunningham (4 times), and Bobby Douglass (1972).

Thirty-two year-old Adrian Peterson had 37 carries last week against the 49ers, the most rushing attempts for any player over 30 in NFL history. Only one player since the merger has recorded 30+ carries in back-to-back games at Peterson's age: John Riggins, who did so at age 35 in 1984.

The 2017 Jaguars have the NFL's top scoring defense, allowing only 14.6 points per game. Since 1994, 26 teams have allowed fewer than 15 points per game over a full season. All 26 of those teams made the playoffs.

The last time the Packers played the Bears without Aaron Rodgers or Brett Favre as their starting QB was Week 15, 1991, when Jim Harbaugh led the Bears past Mike Tomczak & the Packers 27-13, earning a W for head coach Mike Ditka.

Good news for the 6-2 Steelers: Pittsburgh started 6-2 or better in each of its six Super Bowl-winning seasons (1974, 1975, 1978, 1979, 2005 and 2008). Also good news: Since 2014, the Steelers are 19-5 in the second half (last 8 games) of the season, best in the NFL.

Eli Manning will make his 208th consecutive start Sunday, having started every game since Week 11, 2004 for the Giants. Manning will tie his brother Peyton and Hall of Fame linebacker Derrick Brooks for the 5th-longest consecutive starts streak since 1991.