Bad news for Deshaun Watson and the Texans: No rookie QB has gone into New England and beaten the Patriots since Bill Belichick took over as head coach in 2000. Those rookies are 0-8 with 5 TD, 16 INT, and a 50.7 passer rating.

Matt Ryan has thrown 23 passing touchdowns since his last interception (including playoff games) back in Week 13 of 2016. No player has thrown 25 passing touchdowns without a pick since Tom Brady, en route to MVP honors in 2010 (26 straight).

Dak Prescott and Dez Bryant have not been on the same page this season for the Cowboys. Prescott has thrown 2 interceptions when targeting Bryant, and his 29.1 passer rating when targeting #88 is 4th-lowest in the NFL among all QB-receiver duos with at least 10 targets.

Dalvin Cook seemingly gets stronger as the game progresses. This season, he is averaging 0.7 yards per carry in the 1st quarter, 2.9 yards per carry in the 2nd quarter, 7.5 yards per carry in the 3rd quarter, and an NFL-high 9.1 yards per carry in the 4th quarter.

Kareem Hunt compares quite favorably with the NFL�s last leading rookie rusher through 2 career starts. Hunt has gained more than twice as many scrimmage yards (355 to 139) and scored more than twice as many touchdowns (5 to 2) as Ezekiel Elliott did in his first two NFL games.

The 49ers offense has struggled in 2017, but Carlos Hyde has been a bright spot. In fact, Hyde is responsible for 43.8 percent (220/502) of the 49ers� scrimmage yards this season, the highest percentage of any player in the NFL.

The Broncos have not lost a game in September since 2014, winning 8 straight (longest active streak). QB Trevor Siemian is 5-0 with 100.2 passer rating in the league�s opening month, and 5-6 with an 81.9 rating in all other months.

Aaron Rodgers has defeated 30 of the 31 NFL teams he has faced in his career, with the lone exception of the Bengals. A win over Cincinnati would make him the 7th QB to beat 31 different teams, joining Brett Favre (32), Peyton Manning (32), Tom Brady, Drew Brees, Ben Roethlisberger and Kerry Collins.

The Panthers defense has been stout through two games and are the only team in the NFL to not allow an offensive touchdown this season. It's the first time in team history that the Panthers have not allowed a touchdown through two games and the first time since 2006 that the Panthers have held two opponents to three or fewer points in an entire season.

Marshawn Lynch has allowed the Raiders offense to feature a more balanced attack, running the ball on 47.5 percent of plays (8th-highest in NFL), compared to 40.7 percent of plays in 2016 (15th-highest). In Week 2 against the Jets, the Raiders offense totaled 180 rushing yards and 3 touchdowns. The Raiders reached 180+ rushing yards in just 2 games from 2014-2016. They will be facing a Redskins defense that has allowed 75 rushing yards per game this season (9th-fewest in the NFL).