The Chiefs and Rams will be the 11th meeting in NFL history to feature two teams each averaging 33.0+ PPG entering the game (Week 4 or later), and it will be the first such game in Week 10 or later. The teams' combined 68.8 PPG is the most combined PPG by opponents entering a game in Week 10 or later in the Super Bowl era.

Andrew Luck is 9-0 in his career against the Titans, his most wins against any opponent. Since 1970, only Hall of Famer John Elway (10-0 in career against the Patriots) has more wins without a loss against a single opponent than Luck against the Titans.

The Bears currently have the best turnover differential in the NFL (+13). The last time the Bears led the NFL in TO differential? In 1985, when the "Monsters of the Midway" won the Super Bowl.

How dominant has the running back duo of Alvin Kamara & Mark Ingram been for New Orleans? Since 2017, "Boom and Zoom" have combined for 2,683 rushing yards, more than 10 NFL teams in that span. Kamara and Ingram have scored 42 scrimmage touchdowns since 2017, more scrimmage TD than both the Cardinals and Bills in that span.

Nick Chubb (32.90), Christian McCaffrey (31.80), Ezekiel Elliott (30.70) and David Johnson (30.30) all scored over 30 fantasy points in Week 10. It was the first time that four running backs scored 30+ fantasy points in the same week since Week 1, 2004 when SEA Shaun Alexander (34.60), KC Priest Holmes (32.90), NYJ Curtis Martin (32.30) and DEN Quentin Griffin (31.70). Week 10 was only the fifth time that 4 running backs scored 30+ fantasy points in the same week since at least 2000.

The Fountain of Youth must reside in Washington. Adrian Peterson has averaged 93.3 scrimmage YPG this season, which puts him on pace for the most scrimmage YPG by a RB older than 33 in a season since the 1970 merger (min. 4 games). The player Peterson would pass: former Redskins player and Hall of Famer John Riggins, who averaged 91.7 scrimmage YPG at age 34 and 91.6 scrimmage YPG at age 35.

Patrick Mahomes leads the NFL in both pass yards (3,150) and pass TD (31), while Todd Gurley leads the NFL in scrimmage yards (1,390) and scrimmage TD (17). This game will mark the first time since at least the 1970 merger that the NFL's leader in pass yards and pass TD faced off against the leader in scrimmage yards and scrimmage TD.

Matt Ryan has the 4th-highest passer rating in the NFL (113.2) this season, while the Cowboys defense enters the game with the NFL's number three scoring defense (19.0 PPG allowed). Therein lies the problem for Ryan: since 2011, Ryan is 1- 11 with 19 TD and 16 INT against Top 3 scoring defenses (in Week 4 or later).