Hilton had 16 receptions of 25 yards or more in 2018, leading the NFL in receiving yards (951) from Week 8 to Week 17. During those weeks, the Colts went 8-1. Hilton's 199-receiving yard game in Week 14 was the fifth-best in the NFL in 2018.

Matt Ryan was one of three quarterbacks to throw 30-or-more touchdown passes and single-digit interceptions. Ryan has thrown for 4,000+ yards in eight consecutive seasons, the longest active streak in the NFL.

Lindsay was the only player in the NFL with 1,000+ rush yards on fewer than 200 carries during the 2018 season. He is the first player to do that since Jamaal Charles in 2009. Lindsay's 5.4 rush yards per carry was the highest in the NFL by any player with 150+ carries in 2018, earning him a Pro Bowl nod as a rookie.

Dee Ford recorded at least half a sack in 11 games in 2018, tied for the most in the NFL. His seven forced fumbles in 2018 were tied for most in the league.

Ebron's career-high 13 receiving touchdowns led all tight ends, only Antonio Brown (15) had more last season. Ebron became the third player in Colts history with 13 receiving touchdowns in a season, a feat that surpassed his career total of 11 receiving touchdowns entering the season.

Pierre-Paul logged 12.5 sacks in 2018, his highest total since 2014 and tied for the 12th most in the NFL. Pierre-Paul is one of three active players (along with Chandler Jones and Khalil Mack) to record 12.0+ sacks in a season with two different franchises (Tampa Bay Buccaneers and New York Giants).

Amari Cooper became the first player in the last five seasons with 200+ receiving yards and 3+ receiving touchdowns in a game in Week 14, 2018. Cooper's 217-yard performance in Week 14 was the most receiving yards in a game in 2018. He was named to the 2019 Pro Bowl, his third selection in four seasons.

In 2018, Jadeveon Clowney was one of four players in the NFL to record at least 1.0 sack, force 1+ fumbles, recover 1+ fumbles and have 1+ passes defended in a single game in 2018. Clowney became the third player in Texans franchise history with 60 career tackles for a loss and 60 career QB hits, joining J.J. Watt and Mario Williams. His selection to the 2019 Pro Bowl made him the fifth player in Texans franchise to be selected to three consecutive Pro Bowls.

Taking the place of Le'Veon Bell, James Conner totaled 1,470 scrimmage yards (6th among RBs) and 13 scrimmage touchdowns. He had the largest increase in scrimmage yards (+1,326) and scrimmage touchdowns (+13) from 2017. James Conner's 20.8 touches per game last season ranked fourth, behind only Ezekiel Elliott, Todd Gurley, and Saquon Barkley.

Jaylon Smith was one of only five players with 120+ tackles and 4.0+ sacks. He totaled 14 hustle stops (20+ yards covered before tackle).