Alex Smith has thrown 16 touchdown passes and no interceptions on 259 pass attempts this season. He needs 5 more pass TD without an INT to break Peyton Manning's 2013 record for most pass TD prior to a player's first INT in a season (20).

No quarterback has more wins than Alex Smith or Dak Prescott since the start of last season (17 apiece). Tom Brady also boasts 17 wins in that span.

This game features a matchup of the NFL's last two MVP winners, Matt Ryan (2016) and Cam Newton (2015). In their MVP seasons, Ryan and Newton combined for a 26-6 record, 73 passing touchdowns, and 17 interceptions. Since their MVP season, they have combined for a 15-14 record, 38 passing touchdowns, and 31 interceptions.

If Carson Wentz does indeed go on to win MVP as many have predicted after Week 8, he would join some lofty company. The only players to win an MVP award within their first 2 NFL seasons all reside in Canton: Kurt Warner (1999), Dan Marino (1984), Earl Campbell (1978), and Jim Brown (1957 & 1958).

If recent history is any indication, count on the Seahawks to extend their 4-game winning streak. No team has a better record in November than the Seahawks' 15-4 mark since 2012, when Russell Wilson joined the team. Wilson's 106.9 passer rating is the highest of any QB in November since 1970 (min. 300 attempts) -- and the 2nd-highest of any QB in any month with at least 300 attempts (Aaron Rodgers, 108.1 in October).

Will Marcell Dareus help an already-impressive defense become even more dominant? The Jaguars traded for the 2-time Pro Bowler after posting 33 sacks in their first 7 games this season -- most in the NFL and the same total as Jacksonville's entire 2016 campaign. The Jaguars are on pace for 75 sacks, which would break the NFL single-season record of 72, held by a 1984 Bears team featuring Hall of Famers Mike Singletary, Richard Dent & Dan Hampton.

As a rookie, Eli Manning went 1-6 with 6 TD, 9 INT, a stat-line eerily similar to Jared Goff's rookie season (0-7 record, 5 TD, 7 INT). In Year 2, Manning rebounded to go 11-5 and improved his passer rating by over 20 points. This season, Jared Goff is on pace to go 11-5 and improve his passer rating by over 20 points.

Josh McCown has thrown 2+ passing touchdowns in each of the last 4 games. With 2+ pass TD on TNF, he'd become the first Jets QB since Joe Namath (1967- 68) to have 2+ pass TD in 5 consecutive games.

Deshaun Watson leads the NFL with 19 touchdown passes this season (tied with Carson Wentz) and is on pace to throw 43. He could become the first rookie to lead the NFL in passing touchdowns in the Super Bowl era and would smash the rookie passing TD record by 17 (Peyton Manning & Russell Wilson, 26).