Details: Saturday, 7 p.m. ET, ESPN
What's at stake? Bret Bielema's job, for one thing. No, he's not at risk to be fired after a loss here, but after two embarrassing non-conference losses, every week is a referendum on his future in Fayetteville. And with another game against the offense Bielema hates -- the spread -- it's a referendum on Bielema's smash-mouth ground game as well.
Matchup to watch: Texas A&M DE Myles Garrett vs. Arkansas OL Denver Kirkland
Game picks:
Brandt: Texas A&M, 31-28
Brooks: Texas A&M, 34-28
Davis: Texas A&M, 50-40
Goodbread: Texas A&M, 38-17
Jeremiah: Arkansas, 31-30
Reuter: Texas A&M, 34-28
Zierlein: Texas A&M, 28-20

Details: Saturday, 3:30 p.m. ET, ESPN
What's at stake? The Longhorns' offensive identity. Texas lost again last week, but appears to have found a quarterback in freshman Jerrod Heard. If he can get it done in a conference game the way he did against Rice and Cal, Charlie Strong might have a cornerstone on which to build a better team.
Matchup to watch: Oklahoma State DB Jordan Sterns vs. Texas QB Jerrod Heard
Game picks:
Brandt: Oklahoma State, 31-30
Brooks: Texas, 38-37
Davis: Oklahoma State, 44-41
Goodbread: Texas, 27-21
Jeremiah: Texas, 28-24
Reuter: Oklahoma State, 27-24
Zierlein: Texas, 28-24

Details: Saturday, Noon ET, ESPN2
What's at stake? Nobody in the ACC's Coastal Division has played a conference game yet, so for both schools it's a chance to break out of the standings gate in what should be a wide-open divisional race. Georgia Tech's triple-option also looks to rebound from a weak showing at Notre Dame.
Matchup to watch: Georgia Tech QB Justin Thomas vs. Duke DB Jeremy Cash
Game picks:
Brandt: Georgia Tech, 30-20
Brooks: Georgia Tech, 27-20
Davis: Georgia Tech, 35-27
Goodbread: Georgia Tech, 35-21
Jeremiah: Georgia Tech, 21-20
Reuter: Georgia Tech, 31-20
Zierlein: Georgia Tech, 30-20

Details: Saturday, 3:30 p.m. ET, CBS
What's at stake? It's already becoming clear that Georgia is the team to beat in the SEC East. What's unclear is which team is capable of mounting a challenge. This game will shed some light on Georgia's primary competition.
Matchup to watch: Tennessee WR Preston Williams vs. Florida CB Vernon Hargreaves
Game picks:
Brandt: Florida, 21-20
Brooks: Florida, 13-10
Davis: Tennessee, 42-38
Goodbread: Tennessee, 24-13
Jeremiah: Tennessee, 21-17
Reuter: Tennessee, 28-24
Zierlein: Florida, 28-21

Details: Saturday, 7:30 p.m., ESPN2
What's at stake? Just Auburn's goals for the entire season, on the line before the end of September. Gus Malzahn has benched QB Jeremy Johnson in hopes of avoiding a second SEC loss, which would be devastating to AU's conference title hopes.
Matchup to watch: Mississippi State WR De'Runnya Wilson vs. Auburn CB Jonathan Jones
Game picks:
Brandt: Auburn, 34-31
Brooks: Mississippi State, 17-15
Davis: Mississippi State, 31-24
Goodbread: Mississippi State, 28-20
Jeremiah: Mississippi State, 24-21
Reuter: Mississippi State, 24-17
Zierlein: Mississippi State, 27-24

Details: Saturday, 4:45 p.m. ET, FOX
What's at stake? It's conference opener day all over the Big 12, and the Red Raiders are a confident 3-0 team facing a Horned Frogs defense already decimated by injury. TCU quarterback and Heisman Trophy candidate Trevone Boykin, however, can win a track meet if necessary.
Matchup to watch: TCU WR Josh Doctson vs. Texas Tech DB Justis Nelson
Game picks:
Brandt: TCU, 45-42
Brooks: TCU, 60-52
Davis: TCU, 55-51
Goodbread: TCU, 41-35
Jeremiah: TCU, 45-31
Reuter: TCU, 52-38
Zierlein: TCU, 42-35

Details: Saturday, Noon ET, ABC
What's at stake? Jim Harbaugh will either be 3-1 or 2-2 when this one is done, and the latter possibility would foretell a rough season, given that UM hasn't even started conference play yet.
Matchup to watch: BYU MLB Harvey Langi vs. Michigan RB De'Veon Smith
Game picks:
Brandt: Michigan, 24-21
Brooks: BYU, 24-20
Davis: Michigan, 24-21
Goodbread: Michigan, 20-16
Jeremiah: Michigan, 21-17
Reuter: Michigan, 24-21
Zierlein: Michigan, 24-20

Details: Saturday, 10:30 p.m. ET, ESPN
What's at stake? USC can't afford an 0-2 start in Pac-12 play, and Arizona State QB Mike Bercovici is capable of matching Trojans star QB Cody Kessler throw for throw.
Matchup to watch: USC LB Su'a Cravens vs. Arizona State WR D.J. Foster
Game picks:
Brandt: USC, 31-24
Brooks: USC, 27-24
Davis: Arizona State, 40-38
Goodbread: USC, 35-24
Jeremiah: USC, 28-27
Reuter: USC, 35-31
Zierlein: Arizona State, 28-24

Details: Saturday, 8 p.m. ET, ABC
What's at stake? Two 3-0 teams looking to get off to the right start clash in a key battle in the Pac-12 South race. Arizona fans have their fingers crossed that star LB Scooby Wright III will return from injury. He practiced with the first-team defense this week. UCLA fans, meanwhile, were dealt a setback with news of Myles Jack's knee injury.
Matchup to watch: UCLA QB Josh Rosen vs. Arizona LB Scooby Wright III
Game picks:
Brandt: UCLA, 37-30
Brooks: UCLA, 24-23
Davis: UCLA, 35-28
Goodbread: UCLA, 31-30
Jeremiah: UCLA, 35-24
Reuter: Arizona, 45-41
Zierlein: UCLA, 28-27
Note: Predictions were submitted prior to the announcement of Jack's season-ending injury.

Details: Saturday, 8:30 p.m. ET, FOX
What's at stake? With one loss already, Oregon's hopes for a college football playoff berth are now at stake every week. The good news: QB Vernon Adams, who sat out last week's game with a finger injury, is expected back.
Matchup to watch: Utah RB Devontae Booker vs. Oregon LB Joe Walker
Game picks:
Brandt: Oregon, 38-28
Brooks: Oregon, 33-30
Davis: Oregon, 45-40
Goodbread: Oregon, 45-31
Jeremiah: Oregon, 31-27
Reuter: Oregon, 38-24
Zierlein: Oregon, 33-24