The skinny: Washington State is coming off a heartbreaking loss to Cal in which quarterback Connor Halliday (above) had the most prolific performance of any signal-caller last week. He will have to turn things around quickly against a Stanford defense that's ranked second in the country and will provide a much stiffer test than anything he's seen before. Cardinal receiver Ty Montgomery (above) had an off day against Notre Dame last week, but he should have a field day against the Cougars' secondary. Stanford has won the last six in the series by an average score of 43-15.
Game picks:
Brandt: Stanford, 34-14

Brooks: Stanford, 24-17
Jeremiah: Stanford, 38-17
Fischer: Stanford, 38-35
Goodbread: Stanford, 35-27
Huguenin: Stanford, 34-21

Details: Saturday, 3:30 p.m. ET, ESPNU
The skinny: Clemson looks to be the ACC's second-best team, which could get the Tigers into the Orange Bowl. Both teams have pass-rush standouts: Clemson DE Vic Beasley (above) and Louisville LB Lorenzo Mauldin (above). Clemson leads the ACC in total offense and scoring offense, and Louisville leads in total defense and scoring defense, so it will be strength vs. strength. Tigers true freshman QB Deshaun Watson has accounted for 15 TDs. Louisville's offense has been inconsistent; perhaps the expected return of star WR DeVante Parker from injury will help. Clemson is 18-2 in its last 20 home games against ACC teams.
Game picks:
Brandt: Clemson, 30-20
Brooks: Louisville, 35-31
Jeremiah: Clemson, 28-21
Fischer: Clemson, 33-13
Goodbread: Louisville, 28-24
Huguenin: Clemson, 24-16

Details: Saturday, 12 p.m. ET, ABC
The skinny: No matter the records, there's just something special about the "Red River Shootout" between Oklahoma and Texas with a Cotton Bowl divided down the middle between burnt orange and crimson. Both teams are coming off Big 12 losses and looking to get back on track in 2014. Tyrone Swoopes (above) faces his toughest defense of the season as he tries to get the Longhorns' offense going, while Sooners signal-caller Trevor Knight (above) is trying to put last week's mistakes behind him and return to form.
Game picks:
Brandt: Oklahoma, 30-13

Brooks: Oklahoma, 31-24
Jeremiah: Oklahoma, 41-28
Fischer: Oklahoma, 31-10
Goodbread: Oklahoma, 40-23
Huguenin: Oklahoma, 31-14

Details: Saturday, 6 p.m. ET, ESPN
The skinny: This one will be won and lost on the line of scrimmage, just the way both teams like it. Although Alabama's offense clearly has the better passing attack, expect an old-school slugfest controlled by the better rushing attack. Alabama freshman Cam Robinson (above) has emerged into one of the SEC's top left tackles, and he will get a stiff test in Arkansas defensive end Trey Flowers (above). Alabama will miss center Ryan Kelly, who is out with an injury. The last time Alabama visited Arkansas, the Tide won 52-0 in the largest margin of victory since 1948.
Game picks:
Brandt: Alabama, 31-14
Brooks: Alabama, 28-20
Jeremiah: Alabama, 17-16
Fischer: Alabama, 38-20
Goodbread: Alabama, 28-17

Huguenin: Alabama, 34-21

Details: Saturday, 10:30 p.m. ET, ESPN2
The skinny: Tucson will be pumped to see the Wildcats back in action after beating Oregon last week. Arizona has a chance to really take hold in the Pac-12 South with a win over USC. Freshman quarterback Anu Solomon (above) has looked like a savvy veteran under center and has a number of weapons on the outside to get the ball to. USC might be able to move the ball on offense, but it's the defense -- led by Leonard Williams (above) -- that will have to step up if the Trojans have any shot of winning.
Game picks:
Brandt: Arizona, 31-28
Brooks: Arizona, 35-32
Jeremiah: Arizona, 28-27

Fischer: Arizona, 34-28

Goodbread: USC, 24-20

Huguenin: Arizona, 35-31

Details: Saturday, 12 p.m. ET, CBS
The skinny: Georgia standout freshman Nick Chubb (above) figures to get his first career start, or at least his most extensive playing time, with his path cleared by suspension (Todd Gurley) and injury (Keith Marshall). The most dynamic players on Missouri's defense -- defensive ends Shane Ray (above) and Markus Golden -- are better suited for rushing the passer than stopping the run. Tigers quarterback Maty Mauk looked awful in his last outing against South Carolina. Young, underrated talent to watch: Missouri sophomore cornerback Aarion Penton.
Game picks:
Brandt: Missouri, 27-24

Brooks: Missouri, 28-21

Jeremiah: Georgia, 30-27

Fischer: Georgia, 26-20
Goodbread: Georgia, 23-13
Huguenin: Missouri, 23-20

Details: Saturday, 3:30 p.m. ET, FOX
The skinny: A week ago this looked like a top-10 showdown at the Rose Bowl. Now it's a pair of teams coming off losses and still trying to stay afloat in their respective Pac-12 divisions. There will still be plenty of NFL scouts on hand to see a fascinating matchup of Marcus Mariota (above) against Brett Hundley (above), who could be-10 top picks in the draft. Beware, however, as each team has had serious issues along the offensive line -- Oregon is playing a true freshman at tackle -- and it could be a long night for each of the quarterbacks. The visiting team has won just one of the past seven in this series.
Game picks:
Brandt: UCLA, 34-31

Brooks: Oregon, 35-30
Jeremiah: UCLA, 34-31
Fischer: Oregon, 40-31
Goodbread: Oregon, 45-35

Huguenin: Oregon, 34-28

Details: Saturday, 3:30 p.m. ET, ABC
The skinny: An old rivalry is renewed once again in Waco with perhaps the biggest stakes in the series in decades. Trevone Boykin (above) and TCU are fresh off a huge upset win over Oklahoma but hit the road for the second time of the season to face a hostile crowd. Bryce Petty (above) is hoping to clean up some offensive sluggishness Baylor had last week in order to stay atop the Big 12 and keep alive the Bears' playoff hopes.
Game picks:
Brandt: Baylor, 38-31

Brooks: TCU, 32-31

Jeremiah: Baylor, 38-28
Fischer: Baylor, 33-31

Goodbread: Baylor, 27-10
Huguenin: Baylor, 45-38

Details: Saturday, 9 p.m. ET, ESPN
The skinny: A salty Ole Miss defense will have to be on point against Texas A&M's high-flying passing attack. The Rebels have the best secondary in the SEC, but will be without a key member for the first half (Trae Elston, suspension). Up front, the battle between Ole Miss' Robert Nkemdiche (above) and Aggies guard Jarvis Harrison (above) should prove to be a fun one. With both teams operating from hurry-up, no-huddle offenses, defensive stops will be at a premium.
Game picks:
Brandt: Ole Miss, 31-28

Brooks: Texas A&M, 35-31
Jeremiah: Ole Miss, 28-24

Fischer: Texas A&M, 30-28

Goodbread: Texas A&M, 38-21

Huguenin: Ole Miss, 31-27

Details: Saturday, 3:30 p.m. ET, CBS
The skinny: Tigers senior running back Cameron Artis-Payne (above) has picked up where Tre Mason left off last year, rushing for over 100 yards in four of five games this season. Mississippi State linebacker Benardrick McKinney (above) will play a key role in slowing Artis-Payne, who does most of his damage between the tackles. Bulldogs cornerback Jamerson Love will need to play bigger than his size against Auburn receivers Sammie Coates and D'haquille Williams.
Game picks:
Brandt: Auburn, 31-28
Brooks: Auburn, 28-27
Jeremiah: Mississippi State, 24-23
Fischer: Auburn, 37-28
Goodbread: Mississippi State, 26-21
Huguenin: Auburn, 38-31