Details: Saturday, Noon ET, FOX
What's at stake? Baylor draws a West Virginia team wounded by two consecutive losses in Big 12 play, but the Mountaineers' offense can score with anyone. Baylor looks to stay undefeated, and keep pace with TCU and Oklahoma State in the conference race.
Matchup to watch: West Virginia WR Shelton Gibson vs. Baylor CB Xavien Howard

Game picks:
Brandt: Baylor, 52-24
Brooks: Baylor, 62-42
Davis: Baylor, 55-40
Goodbread: Baylor, 45-30
Jeremiah: Baylor, 58-34
Reuter: Baylor, 56-35
Zierlein: Baylor, 51-24

Details: Saturday, 3:30 p.m. ET, ABC
What's at stake? OU tries to rebound from an embarrassing loss to a bad Texas team, and doing so against a Kansas State team that just took TCU to the wire won't be easy. If OU loses here, the Big 12 will most likely come down to TCU, Baylor and Oklahoma State.
Matchup to watch: Oklahoma WR Sterling Shepard vs. Kansas State CB Danzel McDaniel

Game picks:
Brandt: Oklahoma, 31-27
Brooks: Oklahoma, 24-20
Davis: Oklahoma, 38-30
Goodbread: Oklahoma, 28-17
Jeremiah: Oklahoma, 34-28
Reuter: Kansas State, 35-31
Zierlein: Kansas State, 35-31

Details: Saturday, Noon ET, ABC/ESPN2
What's at stake? The Hawkeyes come in at 6-0, and their most impressive wins to date have been Pittsburgh and Wisconsin. Northwestern (5-1) would be every bit as strong a win for Iowa. Look for a low-scoring game here with two defenses that have suffocated opponents when playing their best.
Matchup to watch: Iowa DB Jordan Lomax vs. Northwestern H-back Dan Vitale

Game picks:
Brandt: Northwestern, 20-17
Brooks: Iowa, 16-14
Davis: Northwestern, 21-19
Goodbread: Northwestern, 20-13
Jeremiah: Iowa, 17-13
Reuter: Northwestern, 20-17
Zierlein: Iowa, 24-20

Details: Saturday, 7:30 p.m. ET, NBC
What's at stake? How do the Trojans respond to the termination of coach Steve Sarkisian and the transition to interim coach Clay Helton? The timing couldn't be worse with a road trip to play 14th-ranked Notre Dame. The Fighting Irish defense against the Trojans' offense will have future NFL individual matchups at multiple spots.
Matchup to watch: USC CB Adoree' Jackson vs. Notre Dame WR Will Fuller

Game picks:
Brandt: Notre Dame, 34-27
Brooks: USC, 21-20
Davis: Notre Dame, 40-30
Goodbread: USC, 31-28
Jeremiah: USC, 28-24
Reuter: Notre Dame, 34-24
Zierlein: Notre Dame, 28-20

Details: Owusu makes spectacular grab in win over UCLA
What's at stake? The Cardinal offense has been surging since a sluggish start against Northwestern. Stanford enters here at 3-0 in Pac-12 play. Having already lost to Arizona State, UCLA must win here to stay alive in the Pac-12 South.
Matchup to watch: UCLA DL Kenny Clark vs. Stanford OL Joshua Garnett

Game picks:
Brandt: Stanford, 35-21
Brooks: UCLA, 21-20
Davis: Stanford, 30-21
Goodbread: UCLA, 24-20
Jeremiah: Stanford, 27-17
Reuter: Stanford, 31-21
Zierlein: UCLA, 24-21

Details: Saturday, 10 p.m. ET, ESPN
What's at stake? The Utes are positioning themselves to be among the top four teams in the nation when the College Football Playoff standings are released in a couple of weeks. There is little reason to think ASU can make this upset happen, unless QB Mike Bercovici has a very big night.
Matchup to watch: Utah DB Marcus Williams vs. Arizona State WR/RB D.J. Foster

Game picks:
Brandt: Utah, 31-21
Brooks: Utah, 17-16
Davis: Utah, 35-33
Goodbread: Utah, 35-24
Jeremiah: Utah, 28-27
Reuter: Utah, 38-21
Zierlein: Utah, 31-24

Details: Saturday, 8 p.m. ET, ABC
What's at stake? The Nittany Lions bring a five-game win streak to this one, and for QB Christian Hackenberg, here is a chance to show NFL scouts that he can dissect an elite college defense. The Buckeyes are still finding themselves at the quarterback position as J.T. Barrett could begin settling into a red-zone role.
Matchup to watch: Penn State DE Carl Nassib vs. Ohio State OT Taylor Decker

Game picks:
Brandt: Ohio State, 28-10
Brooks: Ohio State, 20-6
Davis: Ohio State, 48-31
Goodbread: Ohio State, 28-7
Jeremiah: Ohio State, 41-24
Reuter: Ohio State, 35-17
Zierlein: Ohio State, 34-14

Details: Saturday, 3:30 p.m. ET, CBS
What's at stake? Alabama can almost certainly forget about an SEC title if it loses this game, while the Aggies look to avenge a 59-0 loss to the Crimson Tide last year. This could be the best TAMU team Kevin Sumlin has had, and a win here would go a long way to validate that.
Matchup to watch: Alabama OL Cam Robinson vs. Texas A&M DE Myles Garrett

Game picks:
Brandt: Alabama, 31-24
Brooks: Alabama, 20-17
Davis: Alabama, 28-27
Goodbread: Alabama, 31-27
Jeremiah: Texas A&M, 38-31
Reuter: Alabama, 20-17
Zierlein: Texas A&M, 28-21

Details: Saturday, 7 p.m. ET, ESPN
What's at stake? Because it's a cross-divisional game, the stakes in the SEC race here aren't as high as they could be. But both teams are undefeated, and all eyes will be on the Gators' defense and how it will fare against LSU's Leonard Fournette. Also at stake? Whether Florida's offense can sustain without suspended starting QB Will Grier.
Matchup to watch: LSU RB Leonard Fournette vs. Florida LB Antonio Morrison

Game picks:
Brandt: LSU, 27-13
Brooks: LSU, 17-13
Davis: LSU, 38-30
Goodbread: LSU, 28-9
Jeremiah: LSU, 21-13
Reuter: LSU, 24-14
Zierlein: Florida, 24-23

Details: Saturday, 3:30 p.m. ET, ESPN
What's at stake? Who expected Michigan to be ranked No. 12 halfway through the season? New coach Jim Harbaugh can score his first signature win against the rival Spartans, and continue an unlikely push toward the top of the Big Ten. Michigan State has looked beatable this year, but remains unbeaten.
Matchup to watch: Michigan State LB Riley Bullough vs. Michigan RB De'Veon Smith

Game picks:
Brandt: Michigan, 21-20
Brooks: Michigan, 7-3
Davis: Michigan, 24-20
Goodbread: Michigan State, 21-13
Jeremiah: Michigan, 21-17
Reuter: Michigan, 31-24
Zierlein: Michigan, 20-17