NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com's Bobby Kownack breaks down four things to watch for when the Denver Broncos face the Buffalo Bills on "Monday Night Football."

Bills defensive end Von Miller is now out for the season after having surgery to repair his ACL, head coach Sean McDermott announced Wednesday.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

Here are the injuries and news we're monitoring around the league on this Week 11 Sunday.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

The Buffalo Bills will get several key contributors back ahead of Week 17 against the Atlanta Falcons.

With the 2021 NFL season about to kick off, Dan Hanzus unveils his breakdown of the league pecking order entering Week 1. Who's the biggest threat to the Bucs? Which non-playoff team from last season cracks the top 10?

Did Teddy Bridgewater pull into the lead in the Broncos' QB race? Is Micah Parsons the new face of the Cowboys' defense? How did Justin Fields fare in his second pro outing? Gregg Rosenthal identifies the winners and losers of NFL Preseason Week 2.

Stopping today's high-octane offenses is a tough job, but somebody has to do it. Adam Schein projects the top nine NFL defenses in 2021. Who claims the No. 1 spot? Which stout units just missed the cut?

How did the Dolphins' first-round picks fare in Year 1? Did the Patriots snag a solid collection of newbies? Gennaro Filice grades each AFC East team's rookie class.

Buffalo Bills defensive end A.J. Epenesa zooms past New York Jets tackle Tyron Smith en route to powerful sack of quarterback Aaron Rodgers.

Buffalo Bills defensive end A.J. Epenesa's powerful bear-hug tackle yields sack of Jacksonville Jaguars quarterback Trevor Lawerence in their Week 3 matchup.

NFL Network's Mike Garafolo: Bills re-signing DE A.J. Epenesa on two-year contract.

Watch a countdown of the 10 best highlight plays made by the Buffalo Bills in the 2023 NFL season.

Buffalo Bills linebacker A.J. Epenesa intercepts a pass from Kansas City Chiefs quarterback Patrick Mahomes.

Buffalo Bills defensive lineman A.J. Epenesa comes up with a huge fourth quarter sack of Denver Broncos quarterback Russell Wilson.

The Buffalo Bills' defensive front nabs back-to-back sacks of Denver Broncos quarterback Russell Wilson.

Watch a countdown of the 10 best highlight plays made by the Buffalo Bills through the first nine weeks of the 2023 regular season.

Buffalo Bills defenders A.J. Epenesa and Taron Johnson take down Tampa Bay Buccaneers quarterback Baker Mayfield for back-to-back sacks in the fourth quarter of their 'Thursday Night Football' matchup in Week 8 of the 2023 NFL regular season.

Buffalo Bills defensive end A.J. Epenesa gets to New York Giants quarterback Tyrod Taylor for a sack on third down.

Buffalo Bills defensive end A.J. Epenesa wraps up Jacksonville Jaguars quarterback Trevor Lawrence for second sack of game.

Buffalo Bills defensive end A.J. Epenesa's strip sack on Jacksonville Jaguars quarterback Trevor Lawrence prevent Jags' points at end of first half.

NFL analyst Brian Baldinger breaks down the best plays by the Buffalo Bills defense from Weeks 3 and 4 of the 2023 NFL season.

Watch all the top plays from Week 3 of the 2023 NFL season.

Watch the top defensive plays from Week 3 of the NFL 2023 season.

Watch the top touchdowns from Week 3 of the 2023 NFL season.

Watch the Buffalo Bills best plays vs. the Washington Commanders during Week 3 of the 2023 NFL season.

Watch the game highlights between the Buffalo Bills vs. Washington Commanders during Week 3 of the 2023 NFL season.

Watch the Buffalo Bills best defensive plays vs. Washington Commanders during Week 3 of the 2023 NFL season.

Buffalo Bills defensive end A.J. Epenesa turns Bills' fourth INT of Washington Commanders quarterback Sam Howell into 32-yard TD score, giving Bills a 29-0 commanding lead in fourth quarter.

Buffalo Bills defensive end A.J. Epenesa channels Dikembe Mutombo on massive block of Garoppolo's pass.

Watch the Buffalo Bills' top plays vs. the Chicago Bears from Week 3 of the 2023 NFL preseason.

Watch the highlights from the Preseason Week 3 matchup between the Buffalo Bills and the Chicago Bears.

Buffalo Bills defensive end A.J. Epenesa's pass deflection at line of scrimmage seals victory for Bills.

Watch all of the top plays made by the Buffalo Bills against the Pittsburgh Steelers from Week 5 of the 2022 NFL season.