The 2016 No. 1 overall draft pick will take on the 2016 No. 2 overall draft pick when the Philadelphia Eagles take on the L.A. Rams on Sunday. Kevin Patra breaks down the rest of the Week 14 action.

Tyron Smith is this close to returning to the field. The Dallas Cowboys left tackle (back/groin) is expected to play on Thanksgiving Day against the Los Angeles Chargers.

The Packers fell to the Ravens, and in the process, also lost two important defenders. Safety Ha Ha Clinton-Dix was upset by the play of Ravens center Ryan Jensen, which left a Packer injured.

Case Keenum faces the team that benched him in favor of Jared Goff last season in Sunday's showdown between the Los Angeles Rams and Minnesota Vikings. Kevin Patra breaks down each matchup.

The matchup of the week is ... Saints-Bills? You better believe it! Kevin Patra has everything you need to know for all the matchups as Week 10 approaches.

Seattle Seahawks safety Earl Thomas is doubtful for Thursday's game against the Arizona Cardinals, coach Pete Carroll said. Who else is dealing with injuries heading into Week 10?

Safety Earl Thomas has been ruled out for the Seattle Seahawks on Sunday due to a nagging hamstring injury. Who else might not play this week?

Here's a team-by-team rundown of every player cut as NFL general managers trim their rosters to the mandatory 53-player limit by Saturday's 4 p.m. ET deadline.

The 49ers have signed Vance McDonald to a five-year extension through the 2021 season. The new deal is worth $35 million, a source informed told NFL Network Insider Ian Rapoport.

Week 12 features plenty of intriguing matchups, including what should be a riveting battle between Julio Jones and Patrick Peterson. Kevin Patra previews this week's remaining games.

Sean Lee's practice status for Tuesday is up in the air. The linebacker is dealing with a knee issue, though head coach Jason Garrett doesn't believe it's a long-term problem.

The Cardinals look to be the team to beat in the NFC West, but can the revamped Seahawks present a challenge? Gregg Rosenthal takes a look at the division's rosters.

With Aldon Smith suspended, the San Francisco 49ers are entering September minus a pair of All-Pros on defense. Does that put the team in danger of missing the postseason?

The 49ers announced a two-year contract extension for nose tackle Glenn Dorsey on Tuesday. Can the team count on the injured run-stuffer to contribute in 2014?

The preseason schedule began in earnest with six games Thursday. Michael Vick, Carlos Hyde and De'Anthony Thomas all impressed. Around The League recaps it all right here.

San Francisco 49ers nose tackle Glenn Dorsey likely is out for the 2014 season after tearing his biceps. How big of a blow is this for Vic Fangio's defense?

British Olympian Lawrence Okoye was designated waived/injured by the San Francisco 49ers on Tuesday. Okoye hurt his knee during the team's preseason game Sunday.

The San Francisco 49ers released their physically unable to perform list for the start of training camp. As expected, wide receivers Mario Manningham and Kyle Williams are on the list.