Can't-Miss Play: 59-yard rush! Joe Mixon's gallop vs. Pats marks RB's longest career carry

Houston Texans running back Joe Mixon's gallop 59 yards vs. New England Patriots marks running back's longest career carry.

Philadelphia Eagles quarterback Jalen Hurts drops a 40-yard dime to wide receiver A.J. Brown that ices an Eagles' win vs. the Cleveland Browns.

Houston Texans running back Dameon Pierce gashes Pats for critical score.

Baltimore Ravens running back Derrick Henry rushes for 27 yards against the Washington Commanders.

Tampa Bay Buccaneers running back Bucky Irving's 31-yard run involves stiff-arm, cutback and a block from quarterback Baker Mayfield.

Indianapolis Colts wide receiver Michael Pittman Jr. plays the jump-ball for a 10-yard touchdown against the Tennessee Titans.

Philadelphia Eagles wide receiver DeVonta Smith takes a short completion on a drag route for a 45-yard score to put the eagles up 19-13 vs. the Cleveland Browns midway through the 4th quarter.

New Orleans Saints defensive end Cam Jordan's first INT since 2017 comes via Bresee's deflection.

New England Patriots rookie Drake Maye is perfect on his first career scoring strike.

Cleveland Browns defensive lineman Myles Garrett leaps over the line of scrimmage to block a 57-yard field goal attempt by Philadelphia Eagles kicker Jake Elliott which is then picked up by Browns defensive back Rodney McLeod and returned 50-yards for a game-tying touchdown before the halftime whistle.

New Orleans Saints wide receiver Rashid Shaheed rushes 54 yards for punt-return score vs. Tampa Bay Buccaneers.

Tampa Bay Buccaneers safety Antoine Winfield's fumble recovery and 58-yard touchdown ends quarterback Spencer Rattler's first drive with the New Orleans Saints.

Chicago Bears quarterback Caleb Williams scrambles all over the place before 26-yard dart to tight end Cole Kmet.

Chicago Bears tight end Cole Kmet trucks a man en route to first TD of Jags-Bears matchup on 31-yard grab.

San Francisco 49ers rookie running back Isaac Guerendo saves his career-long rush for the perfect time as he races 76 yards to put icing on the 49ers' "Thursday Night Football" win over the Seattle Seahawks

Seattle Seahawks wide receiver Laviska Shenault Jr.'s 97-YARD touchdown on a kickoff return sends the Lumen Field crowd into a frenzy.

San Francisco 49ers wide receiver Deebo Samuel Sr. breaks free for a 76-yard touchdown on quarterback Brock Purdy's launch downfield.

Big-man INT! New Orleans Saints defensive tackle Khalen Saunders rumbles 35 yards after a HUGE defensive play.

43-yard touchdown! New Orleans Saints quarterback Derek Carr fires deep to wide receiver Rashid Shaheed to put six on the board for the Saints.

Dallas Cowboys quarterback Dak Prescott's CLUTCH fourth-down touchdown to Jalen Tolbert ices his team's 'Sunday Night Football' win over the Pittsburgh Steelers.

New York Giants linebacker Isaiah Simmons comes right through the middle of the Seattle Seahawks field goal team to block a game-tying kick off the foot of Seahawks kicker Jason Myers, and Giants wide receiver Bryce Ford-Wheaton returns it for a game-sealing touchdown.

Las Vegas Raiders tight Jakobi Meyers' toe-tap catch offers cinematic ending to quarterback Aidan O'Connell's sideline dime.

Arizona Cardinals Kyler Murray magic! Kyler and wide receiver Marvin Harrison Jr. team up for pivotal conversion vs. San Francisco 49ers.

New York Giants quarterback Daniel Jones and wide receiver Darius Slayton connect for the second time on the same drive, this time for a 30-yard touchdown that gives the Giants a 16-10 lead vs. the Seattle Seahawks.

Can't-Miss Play: Pick-six touchdown! Los Angeles Rams rookie safety Jaylen McCollough turns Green Bay Packers quarterback Jordan Love's pass into a score for the Rams