In their first practice of the week, 49ers QB Brock Purdy (shoulder soreness) will be limited, while TE George Kittle (hamstring) said he'll be playing vs. the Packers after missing Week 11. 

Buccaneers receiver Mike Evans (hamstring) is trending toward returning for Tampa Bay's Week 12 date with the Giants, coach Todd Bowles told reporters Wednesday.

Should two Chiefs running backs be in your lineup this week? How about Jonathon Brooks in his NFL debut? Check out all of Michael F. Florio's RB starts and sits for Week 12 of the NFL fantasy football season.

How will Justin Herbert follow his massive performance against the Bengals in another prime-time outing? Check out all of Michael F. Florio's QB starts and sits for Week 12 of the NFL fantasy football season.