Nelson injured his quad early in last week's loss to the Falcons.
Teammate Bryan Bulaga (ankle) is also expected to play.
Other injury news we are keeping an eye on this Sunday in Week 3 of the 2017 season:
- New York Giants cornerback Janoris Jenkins (ankle) will play against the Philadelphia Eagles.
- Washington Redskins cornerback Josh Norman (shoulder) is optimistic he will play against the Oakland Raiders on Sunday night, while tight end Jordan Reed (rib, sternum) remains a game-time decision, per Rapoport.
- Carolina Panthers quarterback Cam Newton (shoulder, ankle) is active and will play against the Saints.
- Baltimore Ravens wide receiver Jeremy Maclin left in the first half of Sunday's game against the Jacksonville Jaguars after suffering a concussion but was cleared to return in the second half.
- New England Patriots tight end Rob Gronkowski (groin), cornerback Stephon Gilmore (groin), wide receivers Danny Amendola (concussion), Chris Hogan (knee) and Phillip Dorsett (knee) are all active to play against the Texans. Linebacker Dont'a Hightower (knee) has been ruled out.
- Miami Dolphins running back Jay Ajayi (knee), wide receivers Jarvis Landry (knee) and DeVante Parker (ankle) are all active to play against the Jets.
- Tennessee Titans running back DeMarco Murray (hamstring) is expected to play against the Seattle Seahawks, barring a setback, per Rapoport.
- Los Angeles Chargers running back Melvin Gordon, who experienced knee soreness earlier in the week, is expected to play against the Kansas City Chiefs, a source tells Rapoport.
- Houston Texans running back Alfred Blue (ankle) is active for Sunday's game against the Patriots.
- Seattle Seahawks tight end Jimmy Graham (ankle) is expected to play against the Titans in Nashville, according to Rapoport.
- Detroit Lions pass-rusher Ziggy Ansah (knee) is active for Sunday's game against the Falcons.
- Denver Broncos left tackle Garett Bolles (leg) is active to play against the Bills.
- Indianapolis Colts wide receiver Kamar Aiken (hip) is expected to play against the Cleveland Browns, according to Rapoport.
- Philadelphia Eagles wide receiver Torrey Smith (illness) is expected to play against the Giants while safety Rodney McLeod (hamstring) is a much longer shot, per Rapoport.
- Tampa Bay Buccaneers defensive tackle Gerald McCoy (ankle) is active for Sunday against the Vikings.
- New Orleans Saints defensive tackle David Parry was carted back to the locker room, per Larry Holder of the Times-Picayune.